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The FDA’s Concerning Approval Of New Alzheimer’s Drug, Aduhelm

Aduhelm, a new Biogen drug, received approval from the U.S. Food and Drug Administration (FDA) last week, with the hope that it will be a game-changer when it comes to caring for dementia patients. It is the first federally-approved drug that works to slow the biological process of Alzheimer’s instead of simply alleviate the symptoms. 

Advocates believe that Aduhelm can slow disease progression, ultimately turning Alzheimer’s into a manageable chronic condition. Proponents, however, argue that the scientific evidence fails to support the claims of the drug. Considering this lack of evidence, they also balk at the $56,000 price tag on a year’s worth of treatment. 

Scientists have expressed shock towards the FDA’s decision, especially because the agency ignored an outside advisory committee that voted almost unanimously against approval. Harvard Medical School Professor Aaron Kesselheim was one of three committee members who resigned in protest. He called the decision “probably the worst drug approval…in recent U.S. history.”

Widespread Reach of Aduhelm’s Approval

The cost of Aduhelm, coupled with the number of Americans who could end up using the drug, may have an even more widespread reach and play a role in the ongoing debate about reforming the FDA and enacting legislation to drive down the price of prescription drugs. Industry advocates worry that giving the government more power within the pharmaceutical industry will result in fewer medical breakthroughs. However, Aduhelm’s approval may show this line of thinking to be flawed. The FDA’s concerning approval of the drug may result in less productive future research, a longer wait for successful Alzheimer’s treatment, and more difficulties in funding programs that these patients and their families need.

For more information about the approval of Aduhelm, contact us today.

Additional Reading:

U.S. Food and Drug Administration Approval Process

Zantac Relaunches With New Name and Ingredient After Recall Due to Increased Cancer Risk

In April 2020, the Food and Drug Administration (FDA) issued a recall of all prescription and over-the-counter (OTC) versions of ranitidine, more commonly known as Zantac, due to an increased cancer risk. Recently, the medication relaunched with a new name and ingredient: Zantac 360 (famotidine). The oral tablet is available in two strengths (10 mg and 20 mg) and without a prescription. It is only recommended for use by adults and children over the age of 12. 

Famotidine and ranitidine are in the same class of medications. They are both H2 blockers and work equally well to combat heartburn, acid reflux, and other stomach ailments. After discovering that ranitidine contained a chemical called N-nitrosodimethylamine (NDMA), the FDA tested other H2 blockers for the carcinogen. Fortunately, famotidine has no traces of NDMA. Thus, these is no possible link to cancer, which means that Zantac 360 is a safer option for consumers.

Famotidine may look familiar: it’s the same active ingredient in Pepcid AC, another OTC heartburn medication, meaning Zantac 360 and Pepcid AC provide the same symptom relief without any benefits over the other. They both work within an hour and last for up to 12 hours.

This relaunch comes at a notable time. In addition to the hundreds of lawsuits that have already been filed against Zantac, a new study in The American Journal of Gastroenterology indicates that Zantac products may cause a 22 percent increase in the user’s risk of bladder cancer. 

For more information about the Zantac recall and relaunch, contact us today.

Additional Reading:

Zantac Cancer Claims Invalid Under Federal Law

Zantac Lawsuits & Updates

Zantac (Ranitidine) Commonly Asked Questions

Zantac Cancer Risk

FDA to Reconsider Approvals for Unproven Cancer Drugs

Annually, the United States approves multiple new uses for cancer drugs based on early evidence that they can shrink or slow the spread of tumors. How often do these initial results equate to longer, more robust lives for patients though? At the end of April, the Food and Drug Administration (FDA) met for the first time in a decade to determine if they should revoke the approvals for drugs that have failed to show they extend or improve life after use for cancer treatment. 

During the three-day meeting, the FDA examined unproven cancer drugs from Merck, Roche, and Bristol-Myers Squibb. The schedule included presentations from drugmakers as well as opportunities to seek advice from cancer experts. The hope is that, through this examination, the FDA can remove expensive, unproven cancer drugs from the market. As Dr. Ezekiel Emanual, a cancer specialist and bioethicist at the University of Pennsylvania explains, “Doctors are using these drugs and patients are receiving them with all their toxicities and without knowing whether they are actually doing anything. We should not be in a situation where we’re endlessly uncertain.”

There has been an “unprecedented level of drug development” in recent years, with spending on cancer drugs more than doubling since 2013 to over 60 billion dollars annually. The U.S. spends more per person on prescription drugs than any other nation, and new medications can cost as much as 300,000 dollars per year. Unfortunately, the prices have risen faster than patient survival rates. 


For more information about the potential withdrawal of cancer drugs from the market, contact us today.

Novo Nordisk Recalls Samples of Insulin Medication for Diabetes

The Food and Drug Administration (FDA) announced that global healthcare company Novo Nordisk has voluntarily recalled samples of its insulin medication taken for diabetes, a health condition that affects over 34 million people in the United States alone. 

The company recently recalled nearly 1,500 samples of Levemir®, Tresiba®, Fiasp®, NovoLog®, and Xultophy® — all insulin products that are prescribed to lower a diabetes patient’s blood glucose levels. It was also revealed that all recalled items “are packaged in cartons with either a vial, pen-injector (FlexPen® or FlexTouch®) or a cartridge (PenFill®).” The company stresses that use of a recalled product sample may not deliver the correct dosage, possibly leading to “hyperglycemia or hypoglycemia resulting in adverse health consequences ranging from limited to life-threatening.”

The samples were not stored within the correct temperature ranges, which can cause diminished product efficacy. Fierce Pharma reports that the issues occurred during the winter storm power outages in Texas earlier this year as well as due to human error in physician offices. With about 1.5 million samples in-market, this recall affects 0.1 percent of samples from Novo Nordisk. 

For more information about this recall, contact us today.

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